Herpes Simplex-1 As An Additive Risk Factor for Cognitive Decline in Apolipoprotein E4 Carriers Committee:

.............................................................................................................................25 3.0 Introduction..................................................................................................................26 3.1 Methods .......................................................................................................................28 3.1.1 Participants.......................................................................................................28 3.1.2. Protocol ...........................................................................................................28 3.1.3 Health Assessment ...........................................................................................29 3.1.4 HSV-1 Elisa .....................................................................................................29 3.1.5 Genotyping.......................................................................................................30 3.1.6. Risk Assessment .............................................................................................30 3.1.7 Neuropsychological Testing ............................................................................31 3.2 Statistical Analyses ......................................................................................................31 3.3 Results..........................................................................................................................32 3.3.1 Descriptive Statistics........................................................................................32 3.3.2 Risk Level and Executive Domain Score ........................................................35 3.3.3 Risk Level and Verbal Memory Domain Score...............................................37